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Département de pathologie et biologie cellulaire

Dr. Pierre Drapeau

Research on the Nervous System

Office N-535
Tel.: 514 343-7087

p.drapeau@umontreal.ca

 

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Titles and affiliations

N.B. Graduate students can register at McGill University, with which Dr. Drapeau is also affiliated.

interets de recherche liste des publications membres du groupe

 

Development of neural circuits and disease models

As a model for the formation and function of CNS circuits, we are studying the development of the locomotor network in manipulable zebrafish embryos by combining cellular neurophysiology and molecular genetics. We record and image the activity patterns of identified neurons during development in wild-type and genetically modified embryos, including by transgenic over-expression, upon antisense knockdown and in mutations that affect locomotion.

 

 


Our goal is to elucidate the molecular choreography of locomotor network formation and function. We are also using the zebrafish as a model for the validation of mutations of human genes linked to neurological and psychiatric developmental disorders.

 

 



© Département de pathologie et biologie cellulaire, 2011