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It has long been thought that the adult brain is incapable of producing new neurons. Over the past 15 years, however, it has been discovered that the adult mammalian brain does indeed contain neural stem cells, and that these adult neural stem cells continue to produce large numbers of new brain cells in specific locations such as the forebrain and hippocampus. Our current challenges are to understand the basic biology of adult neural stem cells, how they are affected by injury, disease, and aging, and how they can be therapeutically regulated to promote nervous system regeneration. To investigate these questions, we are currently using normal and transgenic mice, stem cell tissue culture, various immunohistological approaches and in vivo strategies. Additional biochemical and molecular techniques strategies are in development.
Strong applications are always considered for summer positions, graduate students, and post-doctoral fellows. At present, we have research projects examining neural stem cells in the context of:
To apply for an interview, please submit your CV and transcripts to firstname.lastname@example.org
For more information, see our external website.
© Département de pathologie et biologie cellulaire, 2011